The opioid epidemic has become an immense problem in North America, and despite decades of research on the most effective means to treat opioid use disorder, overdose deaths are at an all-time high, and relapse remains pervasive. This article highlights knowledge gaps and discusses cannabis's potential to prevent opioid misuse as a palliative alternative; as well as its ability to alleviate opioid withdrawal symptoms and decrease the likelihood of relapse. The compelling natu

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The endocannabinoid (eCB) system is a complex cell-signaling system identified in the early 1990s by researchers exploring THC. The eCB system works in part as a regulator of the LC-NE system, which is composed of stress hormone-synthesizing neurons that send broad projections throughout the central nervous system. Most current medications target specific neurotransmitters that become dysregulated during periods of depression and anxiety. Due to the eCB system’s relationship

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Anxiety is a reaction to stress that can be beneficial in some situations, as it alerts us to dangers and helps us pay attention. Anxiety disorders differ from these normal feelings of nervousness. They are characterized by excessive fear or anticipation of future concerns, muscle tension, and avoidance behaviors. Anxiety disorders are the most common of mental disorders--affecting nearly 30 percent of adults at some point in their lives. A frequently prescribed type of anti-

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